There is a recent report out on an Israeli experiment
 which seems to have reversed two of the cellular processes associated 
with aging — shortening of telomeres and cellular senescence. It used 
hyperbaric oxygen, given daily over a period of months, and the 
effects appear to be large.
It's possible that the result will 
turn out to be mistaken — the confidence intervals for the various 
effects include zero, although most of them are significantly positive. 
It is also possible that the experiment is changing the cellular markers
 and not whatever underlying biology they are associated with. 
The
 obvious next things to do are to repeat the experiment, ideally with 
more subjects and varying the procedure, and to observe the subjects of 
the first experiment to see whether physical effects of aging are being 
reduced. 
But if it's real, it's huge, since the experimental 
results are for humans, not mice, the procedure should be easy to 
duplicate at relatively low cost, and we ought to have much clearer 
results in only a few more years. I've been saying for a long time that 
the cure for aging will probably come in time for my children but not 
for me, but perhaps I was wrong.
I would be interested in comments from anyone here with relevant expertise.
Saturday, November 21, 2020
Evidence that Aging Can Be Reversed
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4 comments:
You should read a review that adds a bit of perspective.
https://www.fightaging.org/archives/2020/11/overhyping-the-effects-of-hyperbaric-oxygen-treatment-on-aging/
Do people at sea level live longer than people at higher altitude?
If you cut off the oxygen entirely, the person will die rather quickly. Ergo....
It is impossible to tell at this stage what it means, but note that there are many competing approach. The Conboys have been making progress at high speed: https://pubmed.ncbi.nlm.nih.gov/32474458/
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