There is a recent report out on an Israeli experiment
which seems to have reversed two of the cellular processes associated
with aging — shortening of telomeres and cellular senescence. It used
hyperbaric oxygen, given daily over a period of months, and the
effects appear to be large.
It's possible that the result will
turn out to be mistaken — the confidence intervals for the various
effects include zero, although most of them are significantly positive.
It is also possible that the experiment is changing the cellular markers
and not whatever underlying biology they are associated with.
The
obvious next things to do are to repeat the experiment, ideally with
more subjects and varying the procedure, and to observe the subjects of
the first experiment to see whether physical effects of aging are being
reduced.
But if it's real, it's huge, since the experimental
results are for humans, not mice, the procedure should be easy to
duplicate at relatively low cost, and we ought to have much clearer
results in only a few more years. I've been saying for a long time that
the cure for aging will probably come in time for my children but not
for me, but perhaps I was wrong.
I would be interested in comments from anyone here with relevant expertise.
Saturday, November 21, 2020
Evidence that Aging Can Be Reversed
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4 comments:
You should read a review that adds a bit of perspective.
https://www.fightaging.org/archives/2020/11/overhyping-the-effects-of-hyperbaric-oxygen-treatment-on-aging/
Do people at sea level live longer than people at higher altitude?
If you cut off the oxygen entirely, the person will die rather quickly. Ergo....
It is impossible to tell at this stage what it means, but note that there are many competing approach. The Conboys have been making progress at high speed: https://pubmed.ncbi.nlm.nih.gov/32474458/
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